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- By Dylan Moreno
- 06 Dec 2025
Phototherapy is clearly enjoying a surge in popularity. You can now buy illuminated devices for everything from complexion problems and aging signs along with muscle pain and gum disease, the latest being a dental hygiene device enhanced with miniature red light sources, described by its makers as “a significant discovery in at-home oral care.” Globally, the sector valued at $1bn last year is expected to increase to $1.8bn within the next decade. There are even infrared saunas available, which use infrared light to warm the body directly, your body is warmed directly by infrared light. Based on supporter testimonials, the experience resembles using an LED facial mask, stimulating skin elasticity, easing muscle tension, alleviating inflammatory responses and chronic health conditions as well as supporting brain health.
“It appears somewhat mystical,” says a Durham University professor, a scientist who has studied phototherapy extensively. Naturally, we know light influences biological functions. Sunlight enables vitamin D production, crucial for strong bones, immune defense, and tissue repair. Sunlight regulates our circadian rhythms, as well, triggering the release of neurochemicals and hormones while we are awake, and signaling the body to slow down for nighttime. Artificial sun lamps are standard treatment for winter mood disorders to elevate spirits during colder months. Clearly, light energy is essential for optimal functioning.
Although mood lamps generally utilize blue-spectrum frequencies, consumer light therapy products mostly feature red and infrared emissions. During advanced medical investigations, including research on infrared’s impact on neural cells, determining the precise frequency is essential. Light constitutes electromagnetic energy, extending from long-wavelength radiation to the highest-energy (gamma waves). Therapeutic light application employs mid-spectrum wavelengths, the highest energy of those being invisible ultraviolet, then the visible spectrum we perceive as colors and then infrared (which we can see with night-vision goggles).
UV light has been used by medical dermatologists for many years to manage persistent skin disorders including eczema and psoriasis. It modulates intracellular immune mechanisms, “and suppresses swelling,” notes Dr Bernard Ho. “Considerable data validates phototherapy.” UVA reaches deeper skin layers compared to UVB, in contrast to LEDs in commercial products (typically emitting red, infrared or blue wavelengths) “tend to be a bit more superficial.”
Potential UVB consequences, like erythema or pigmentation, are understood but clinical devices employ restricted wavelength ranges – signifying focused frequency bands – that reduces potential hazards. “Therapy is overseen by qualified practitioners, so the dosage is monitored,” explains the dermatologist. And crucially, the lightbulbs are calibrated by medical technicians, “to guarantee appropriate wavelength emission – unlike in tanning salons, where it’s a bit unregulated, and we don’t really know what wavelengths are being used.”
Red and blue light sources, he says, “aren’t really used in the medical sense, but they may help with certain conditions.” Red LEDs, it is proposed, help boost blood circulation, oxygen absorption and dermal rejuvenation, and stimulate collagen production – an important goal for anti-aging. “The evidence is there,” comments the expert. “However, it’s limited.” In any case, amid the sea of devices now available, “it’s unclear if device outputs match study parameters. Optimal treatment times are unknown, how close the lights should be to the skin, the risk-benefit ratio. There are lots of questions.”
One of the earliest blue-light products targeted Cutibacterium acnes, bacteria linked to pimples. Scientific backing remains inadequate for regular prescription – even though, notes the dermatologist, “it’s commonly used in cosmetic clinics.” Certain patients incorporate it into their regimen, he observes, though when purchasing home devices, “we advise cautious experimentation and safety verification. Without proper medical classification, oversight remains ambiguous.”
At the same time, in innovative scientific domains, researchers have been testing neural cells, revealing various pathways for light-enhanced cell function. “Nearly every test with precise light frequencies demonstrated advantageous outcomes,” he states. Multiple claimed advantages have created skepticism toward light treatment – that it’s too good to be true. Yet, experimental evidence has transformed his viewpoint.
Chazot mostly works on developing drug treatments for neurodegenerative diseases, however two decades past, a physician creating light-based cold sore therapy requested his biological knowledge. “He created some devices so that we could work with them with cells and with fruit flies,” he says. “I remained doubtful. It was an unusual wavelength of about 1070 nanometres, that many assumed was biologically inert.”
What it did have going for it, nevertheless, was its ability to transmit through aqueous environments, allowing substantial bodily penetration.
Growing data suggested infrared influenced energy-producing organelles. Mitochondria produce ATP for cell function, generating energy for them to function. “All human cells contain mitochondria, even within brain tissue,” explains the neuroscientist, who, as a neuroscientist, decided to focus the research on brain cells. “It has been shown that in humans this light therapy increases blood flow into the brain, which is always very good.”
Using 1070nm wavelength, energy organelles generate minimal reactive oxygen compounds. In low doses this substance, notes the scientist, “activates protective proteins that safeguard mitochondria, preserve cell function and eliminate damaged proteins.”
Such mechanisms indicate hope for cognitive disorders: antioxidant, inflammation reduction, and cellular cleanup – autophagy being the process the cell uses to clear unwanted damaging proteins.
Upon examining current studies on light therapy for dementia, he reports, about 400 people were taking part in four studies, incorporating his preliminary American studies
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